The Complement System in Rheumatoid Synovitis. II. Intracytoplasmic Inclusions of Immunoglobulins and Complement

Influence of splenectomy on immunoglobulins and complement components in major thalassemia

Abstract Introduction: Thalassemia is the most common hereditary anemia in Iran. The aim of this study was to evaluate the humoral immune system and assess the effect of splenectomy on the serum level of immunoglobulins IgG, IgM, and IgA and complement components in patients with major thalassemia. Materials and Methods: This interventional semi-experimental study (before-after) was performed...

Milk immunoglobulins and complement factors.

The importance of colostrum for the growth and health of newborn offspring is well known. In bovine colostrum, the antibody (immunoglobulin) complement system provides a major antimicrobial effect against a wide range of microbes and confers passive immunity until the calf's own immune system has matured. Bovine serum and lacteal secretions contain three major classes of immunoglobulins: IgG, I...

Indirect Complement Fixation in Foot and Mouth Disease. II. Screening of Cattle Serums

the effect of repeated transfusions on immunoglobulins levels and complement components in beta thalassemia major patients

beta thalassemia major patients receive repeated transfusions in order to compensate anemia and use desferal to remove iron overload. comparing immunoglobulins and complement components in the serum of these patients with normal range shows a significant increase (p<0.001) in igg, iga and igm and a decrease in c3c and c4. the regression analysis confirms a relation between the numbers of transf...

Complement System Part II: Role in Immunity

The complement system has been considered for a long time as a simple lytic cascade, aimed to kill bacteria infecting the host organism. Nowadays, this vision has changed and it is well accepted that complement is a complex innate immune surveillance system, playing a key role in host homeostasis, inflammation, and in the defense against pathogens. This review discusses recent advances in the u...